Cart
sales@molnova.com
MMP-12 Inhibitor
CAS No. 1258003-93-8
MMP-12 Inhibitor( MMP408 | MMP12 )
Catalog No. M28533 CAS No. 1258003-93-8
MMP-12 Inhibitor is a selective inhibitor of MMP-12 with IC50s of 2, 160, 320, and 22.3 nM for human, mouse, rat, and sheep MMP-12.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 403 | Get Quote |
|
| 10MG | 608 | Get Quote |
|
| 25MG | 1039 | Get Quote |
|
| 50MG | 1556 | Get Quote |
|
| 100MG | 2336 | Get Quote |
|
| 200MG | Get Quote | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameMMP-12 Inhibitor
-
NoteResearch use only, not for human use.
-
Brief DescriptionMMP-12 Inhibitor is a selective inhibitor of MMP-12 with IC50s of 2, 160, 320, and 22.3 nM for human, mouse, rat, and sheep MMP-12.
-
DescriptionMMP-12 Inhibitor is a selective inhibitor of MMP-12 with IC50s of 2, 160, 320, and 22.3 nM for human, mouse, rat, and sheep MMP-12.(In Vitro):MMP-12 Inhibitor shows weaker activity against human MMP-3, MMP-13, and MMP-14 with IC50s of 351, 120, and 1100 nM.(In Vivo):In mice, MMP-12 Inhibitor (5 mg/kg, p.o.) effectively alleviates rhMMP-12-induced pulmonary inflammatory response by more than 50%.
-
In Vitro——
-
In Vivo——
-
SynonymsMMP408 | MMP12
-
PathwayMetabolic Enzyme/Protease
-
TargetMMP
-
Recptor——
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1258003-93-8
-
Formula Weight420.44
-
Molecular FormulaC19H20N2O7S
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESN(C(OC)=O)C=1C=C2C=3C(OC2=CC1)=CC(S(N[C@H](C(C)C)C(O)=O)(=O)=O)=CC3
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
molnova catalog
related products
-
AGPS-IN-2i
AGPS-IN-2i is a potent and high-affinity inhibitor of alkylglycerol phosphate synthase that controls ether lipid utilization and metabolism in cells, reduces ether lipid levels and cell migration, and promotes proliferation and motility of cancer cells.
-
Histatin 5
Histatin 5 inhibits the activity of the host matrix metalloproteinases MMP-2 and MMP-9 with IC50s of 0.57 and 0.25 μM, respectively. Histatin 5 is a human basic salivary peptide with strong fungicidal properties in vitro.
-
MMP13-IN-3
MMP13-IN-3 is >1000 selective over other MMPs. MMP13-IN-3 is an effective, selective, and orally active MMP-13 inhibitor (IC50=1 nM) for the potential treatment of osteoarthritis.
